Would you like to help eradicate tuberculosis? Learn how you can prevent and treat this serious disease

Authors

  • Gerardo Vázquez-Marrufo Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo https://orcid.org/0000-0002-0655-1503
  • Ma. Soledad Vazquez-Garcidueñas División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo https://orcid.org/0000-0002-0655-1503

DOI:

https://doi.org/10.35830/mcya.vi22.372

Keywords:

preventive therapy, standard treatment, First-line drugs, second-line drugs

Abstract

About a quarter of the world's population, equivalent to 2 billion people, is infected with the bacteria Mycobacterium tuberculosis (MTb) and approximately 5 to 10% of these people will develop tuberculosis (TB) at some point in their life. The risk of the disease manifesting after infection with the bacteria depends on several factors, the most important being the person's immune status, although we cannot leave aside the main drivers of TB, which are malnutrition, poverty, diabetes, smoking and air pollution. All of these factors must be addressed if we want to achieve the goal of ending the threat of TB as a public health problem by 2035 and thus meet the global objective of the World Health Organization (WHO) of achieving health and welfare for the entire population. This goal is part of a sustainable development agenda adopted on September 25, 2015 by world leaders, focused on achieving poverty eradication, protecting the planet and ensuring prosperity for all in 15 years. Even with this dark outlook, it is reassuring to know that TB is preventable and once the first manifestations of the disease develop, it is curable if treated in time and adequately.

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Author Biographies

Gerardo Vázquez-Marrufo, Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo

Profesor Investigador titular C adscrito al Centro Multidisciplinario de estudios en Biotecnología de la Facultad de Medicina Veterinaria y Zootecnia en la UMSNH. Investigador Nacional SNI III. Investigador Estatal Honorífico de Michoacán. Miembro de la American Society of Microbiology. Revisor de múltiples revistas internacionales con factor de Impacto dentro del área de la Microbiología. 

Ma. Soledad Vazquez-Garcidueñas, División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo

Profesora e Investigadora Titular "C" adscrita a la División de Estudios de Posgrado de la facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez en la UMSNH". Investigadora Nacional nivel I. Miembro de la American Society of Microbiology y de la Asociación Mexicana de Microbiología. Investigadora Estatal Honorífica de Michoacán.

 

References

Allué-Guardia, A., García, J. I., & Torrelles, J. B. (2021). Evolution of drug-resistant Mycobacterium tuberculosis strains and their adaptation to the human lung environment. Frontiers in Microbiology, 12, 612-675.

Arbex, M. A., Varella, M. D. C. L., Siqueira, H. R. D., & Mello, F. A. F. D. (2010). Antituberculosis drugs: drug interactions, adverse effects, and use in special situations-part 1: first-line drugs. Jornal Brasileiro de Pneumologia, 36, 626-640.

Chakaya, J., Khan, M., Ntoumi, F., Aklillu, E., Fatima, R., Mwaba, P., ... & Zumla, A. (2021). Global Tuberculosis Report 2020-Reflections on the Global TB burden, treatment, and prevention efforts. International Journal of Infectious Diseases, 113, S7-S12.

Fajardo, A., Martinez-Martin, N., Mercadillo, M., Galán, J. C., Ghysels, B., Matthijs, S., Martínez, J. L. (2008). The neglected intrinsic resistome of bacterial pathogens. PloS one. 3(2): e1619.

Goig, G. A., Cancino-Muñoz, I., Torres-Puente, M., Villamayor, L. M., Navarro, D., Borrás, R., & Comas, I.(2020). Whole-genome sequencing of Mycobacterium tuberculosis directly from clinical samples for high-resolution genomic epidemiology and drug resistance surveillance: an observational study. The Lancet Microbe, 1(4), e175-e183.

Huang, H., Ding, N., Yang, T., Li, C., Jia, X., Wang, G., ... & Chen, F. (2019). Cross-sectional whole-genome sequencing and epidemiological study of multidrug-resistant Mycobacterium tuberculosis in China. Clinical Infectious Diseases, 69(3), 405-413.

Khawbung, J. L., Nath, D., Chakraborty, S. (2021). Drug resistant tuberculosis: a review. Comparative Immunology, Microbiology and Infectious Diseases, 74: 101574. https://doi.org/10.1016/j.cimid.2020.101574

Lan, Z., Ahmad, N., Baghaei, P., Barkane, L., Benedetti, A., Brode, S. K., ... & Menzies, D. (2020). Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data metaanalysis. The Lancet Respiratory Medicine, 8(4), 383-394

Malik, S., Willby, M., Sikes, D., Tsodikov, O. V., & Posey, J. E. (2012). New insights into fluoroquinolone resistance in Mycobacterium tuberculosis: functional genetic analysis of gyrA and gyrB mutations. PloS one. 7(6): e39754.

Martin, C., Aguilo, N., Marinova, D., & GonzaloAsensio, J. (2020). Update on TB vaccine pipeline. Applied Sciences, 10(7), 2632.

Palomino JC, Leao SC and Ritacco V. Tuberculosis 2007. From Basic Science to Patient Care. First Edit. Bourcillier Kamps.com; 2007. p 97-646. Disponible en: http://www.TuberculosisTextbook.com

Rabahi, M. F., Silva, J. L. R. D., Ferreira, A. C. G., TannusSilva, D. G. S., & Conde, M. B. (2017). Tuberculosis treatment. Jornal brasileiro de pneumologia, 43, 472-486.

Rendon, A., Tiberi, S., Scardigli, A., D’Ambrosio, L., Centis, R., Caminero, J. A., & Migliori, G. B. (2016). Classification of drugs to treat multidrug-resistant tuberculosis (MDR-TB): evidence and perspectives. Journal of thoracic disease, 8(10), 2666.

Salehitali, S., Noorian, K., Hafizi, M., & Dehkordi, A. H. (2019). Quality of life and its effective factors in tuberculosis patients receiving directly observed treatment short-course (DOTS). Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 15, 100093.

Sánchez-Pérez HJ, Bernal, D., Torres, O., & Colorado, A.(2021). Tuberculosis en México en tiempos de COVID-19: algunas reflexiones. Enf Emerg 2021;20(3):160-165

Secretaría de Salud (SS). 2023. Boletín epidemiológico Sistema nacional de vigilancia epidemiológica, Sistema Único de Información.

Organización Panamericana de la Salud. 2021.Tuberculosis en las Américas. Informe regional 2020. Washington, D.C.: Licencia: CC BY-NC-SA 3.0 IGO. https://doi.org/10.37774/9789275324479

World Health Organization. (2016). WHO treatment guidelines for drug-resistant tuberculosis. World Health Organization. https://www.who.int/publications/i/item/9789241549639

World Health Organization. (2020a). WHO consolidated guidelines on tuberculosis. Module 1. Tuberculosis preventive treatment. World Health Organization. https://docs.bvsalud.org/biblioref/2021/06/1254264/9789240001503-eng.pdf

World Health Organization. (2020b). WHO consolidated guidelines on tuberculosis: module 4: treatment: drug-resistant tuberculosis treatment: online annexes. https://apps.who.int/iris/bitstream/handle/10665/332678/9789240007062-eng.pdf

World Health Organization. (2020c). WHO operational handbook on tuberculosis: module 1: prevention: tuberculosis preventive treatment. Licence: CC BY-NC-SA 3.0 IGO. https://apps.who.int/iris/bitstream/handle/10665/331525/9789240002906-eng.pdf

World Health Organization. (2022a). Global tuberculosis report 2022. Geneva: World Health Organization; 2022. Licence: CC BY-NC-SA 3.0 IGO. https://www.who.int/publications/i/item/9789240061729

World Health Organization. (2022b). Rapid communication: key changes to the treatment of drug-resistant tuberculosis (No. ). World Health Organization.https://www.who.int/publications/i/item/WHO-UCN-TB-2022-2

Portada Milenaria, Ciencia y Arte No. 22

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Published

2023-12-14

How to Cite

Vázquez-Marrufo, G., & Vazquez-Garcidueñas, M. S. (2023). Would you like to help eradicate tuberculosis? Learn how you can prevent and treat this serious disease. Milenaria, Ciencia Y Arte, (22), 9–13. https://doi.org/10.35830/mcya.vi22.372

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No. 22 (2023)

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